The friends spread their wings and fly; Cristina and Angel announce the date of their wedding; Rachel asks Megan to be her roommate; John takes the necessary steps toward getting his driver's license; Sean is determined to get a tattoo.

While picking out a wedding dress, powerful emotions are brought up for Cristina and Bea, forcing them to examine the advisability of her upcoming marriage; Elena desires to take her relationship with William to the next level, but an embarrassing family dinner threatens to derail it all; On a journey to health and wellness, Megan and John visit the Chopra Center, where both amusement and self-discovery ensue.

Cristina and Angel meet with their wedding planner and learn the art of compromise; Rachel celebrates her birthday in Vegas surrounded by friends and family; Megan searches for an additional source of income to further her goal of financial independence and grow her "Megpire."

Megan and Rachel make the big move into their new place, which presents its fair share of trials and tribulations.

Megan and Rachel adjust to living independently while Kris and Laurie struggle to let go; Amy looks to Kris and Laurie for guidance as the Kellers start to teach Rocco independence; Sean finds comfort in his relationship with Caley, all the while, he and Sandra have conflicting ideas on how to run his t-shirt business, "Seanese."

With the help of some cute fireman and a self-defense class, Rachel and Megan learn to stay safe while living alone; They celebrate their independence with a no drama party; John and Steven get behind the wheel at last.

Cristina and Angel's wedding date quickly approaches; A nervous Cristina reaffirms her commitment to Angel by surprising him with a gift, while Angel takes lessons on being a good husband and prepares to move in with Cristina; And finally, the big day arrives.